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Alternaria alternata rAlt a 1, m229, IgG4 (ASIT monitoring)

Allergy to mold fungi, such as Alternaria alternata, is a common cause of allergic reactions, especially in people with chronic respiratory diseases. The primary allergen of Alternaria alternata is rAlt a 1, which triggers hypersensitivity in most individuals allergic to this type of mold.

Symptoms of Allergy to Alternaria alternata:

  • Nasal congestion, itching, and runny nose
  • Sneezing fits
  • Coughing, wheezing, shortness of breath
  • Difficulty breathing or choking episodes
  • Exacerbation of bronchial asthma symptoms

Mold allergy can be seasonal or year-round, depending on the level of spores in the environment.

Role of IgG4 in Allergy Treatment

Allergen-specific immunotherapy (ASIT) helps reduce the body’s sensitivity to allergens and prevents the development of severe allergic reactions. During therapy, the immune system produces IgG4 antibodies, which compete with IgE and block allergic responses.

An increase in specific IgG4 to rAlt a 1 is a key indicator of successful treatment.

Why Determine Specific IgG4 to rAlt a 1?

Testing with the ImmunoCAP method allows:

  • Objective evaluation of ASIT effectiveness
  • Confirmation of the immune system’s response to treatment
  • Decision-making on continuing, modifying, or discontinuing therapy

If IgG4 levels do not increase, this may indicate insufficient drug efficacy or the need to adjust the treatment approach.

Why Choose This Test?

  • High accuracy and sensitivity of the ImmunoCAP method
  • Possibility of personalized allergy treatment
  • Helps achieve long-term treatment success

Visit our laboratory for specific IgG4 testing to rAlt a 1 and confidently monitor the effectiveness of your treatment