Beta-Cross laps
Beta-Cross laps are a product of the breakdown of collagen, which makes up 90% of the organic part of bone tissue. In other words, when bone destruction occurs, collagen damage occurs inside it, and as a result, a fragment of collagen (Beta–Cross laps) enters the bloodstream.
There are two types of bone resorption (destruction): physiological and pathological. Pathological resorption occurs in cases where there is either a hormonal imbalance or an imbalance of trace elements (mainly calcium and phosphorus). This condition is called osteoporosis.
There are many causes of osteoporosis, as well as risk factors contributing to its occurrence. The manifestations of the disease are increased bone fragility, hence the main clinical picture:
- Decreased growth;
- Back pain in the projection of the spine;
- Stoop and curvature of the spine;
- Pathological fractures characterized by long and severe fusion.
The diagnostic value of a blood test to determine the concentration of Beta-Cross laps lies in the ability to assess the intensity of bone resorption before starting therapy. In the future, the effectiveness of treatment can be controlled, and the positive dynamics will consist of a decrease in resorption – that is, in less intensive self-destruction of bone tissue.
In addition, a positive trend in the form of a decrease in the level of cross-laps can be observed 3 months after the start of treatment, while the densitometric density (ultrasound method) of the bone increases only after 12-24 months.