Cortisone in the blood (chromatography)

Cortisone is a precursor of the glucocorticoid hormone (cortisol) and does not have low activity in its original form. In stressful situations, it is actively produced by the body, being used as a pharmacological agent. The main action of cortisone lies in its powerful anti-inflammatory effect - suppression of immune reactions and inflammation; regulation of metabolic processes, including stabilisation of blood glucose levels; and adaptation to stressful conditions.

Key tasks of cortisone in the human body include: suppressing immune responses against inflammation, controlling the body's metabolism and energy balance, and participating in the regulation of homeostasis under stress; it is also widely used for the therapy of autoimmune disorders and minimising immunopathological tissue damage.

The peculiarity of cortisone is that it is an inactive form of the hormone (precursor), which after conversion in the liver becomes active cortisol - a substance with more intense effects on the body compared to its precursor.

Elevated levels are observed in:

• Itsenko-Cushing's disease. 

A decrease in the level is observed when:

• violation of metabolic processes; 
• Addison's disease.