Determination of DAO (diamineoxidase) concentration

Suspected Histamine Intolerance

• Chronic skin reactions (urticaria, redness, itching).
• Headaches and migraines.
• Gastrointestinal issues (bloating, diarrhea, abdominal pain, irritable bowel syndrome).
• Symptoms resembling allergies (runny nose, nasal congestion, tearing), but without identified allergens.
• Hypotension or tachycardia after consuming histamine-rich foods (wine, cheese, sausages, seafood).

Diseases in which DAO activity may decrease

• Inflammatory bowel diseases (Crohn’s disease, ulcerative colitis).
• Celiac disease.
• Vitamin B6, copper, and zinc deficiencies.
• Hormonal disorders (changes in estrogen levels, especially during pregnancy or when using oral contraceptives).
• Chronic stress and disturbances in gut microbiota. 

Monitoring the effectiveness of histamine intolerance treatment

• Monitoring the response to a low-histamine diet. 
• Evaluating the efficacy of DAO enzyme therapy.