Package "Molecular Genetic Diagnosis of Prostate Cancer (determination of PCA3 and TMPRSS2 - ERG genes)"
AZF (Azoospermia Factor) is a region on the Y chromosome containing genes that are critical for the development, maturation, and formation of spermatozoa.
Clinical indications:
- Male infertility: in cases of oligozoospermia (low sperm count) or azoospermia (complete absence of sperm).
- Planning assisted reproductive technologies (ART): to assess the chances of obtaining sperm and determining ART tactics.
- Prostate cancer screening: in men at risk (e.g., with a family history of the disease).
Anamnestic indications:
- Family history of male infertility: Presence of cases of unexplained infertility in blood relatives on the male line.
- Family history of prostate cancer: Presence of cases of PC in close relatives, especially at a young age.