Dog rCan f 1, e101, IgG4 (monitoring ACIT)
Dog allergy is a common cause of allergic reactions, manifesting as rhinitis and asthma. The main allergen of dogs is Can f 1, a protein produced by the animal’s salivary and skin glands. This protein triggers allergic reactions in most people sensitive to dogs.
Symptoms of dog allergy:
- Nasal congestion, itching, and runny nose
- Sneezing attacks
- Coughing, shortness of breath, wheezing
- Difficulty breathing or choking episodes
Without timely treatment, allergy can lead to serious complications such as bronchial asthma.
Role of IgG4 in Allergy Treatment
Allergen-specific immunotherapy (ASIT) is the only treatment aimed at eliminating the cause of allergy. During ASIT, the body adapts to the allergen, and the immune system starts producing IgG4 antibodies, which prevent the development of allergic reactions.
An increase in specific IgG4 to Can f 1 during therapy is a key indicator of its effectiveness.
Why Determine Specific IgG4 to rCan f 1?
Monitoring IgG4 levels to the main dog allergen through molecular diagnostics helps to:
- Confirm that the therapy is working and the body is responding to treatment
- Assess the effectiveness of the ASIT medication
- Decide whether to continue, adjust, or replace the therapy
If IgG4 levels do not increase, this may indicate insufficient drug efficacy or the absence of necessary allergen components in the vaccine.
Why Choose This Test?
- The ImmunoCAP method ensures high accuracy and reliability.
- It helps evaluate an individual response to ASIT.
- It improves treatment effectiveness and enhances quality of life.