Timothy grass, g6

Grass pollen is the main cause of respiratory allergic diseases worldwide. The reactivity of IgE to these allergens is manifested in about 40% of allergy sufferers and in 20% of the general population. Timothy grass (Phlum pratense) is one of the most common types of cereals in Northern and Central Europe, producing pollen allergens. It grows best in cooler, wetter and temperate climates and is sown as a pasture.

The allergenicity of Timothy grass is due to the presence of a number of allergens. The molecular and biochemical characterization of P. pretense revealed the presence of several allergen components, such as Phl p 1, 2, 4, 5, 6, 7, 11, 12 and 13. Among these allergen molecules, Phl p 1 is the most important and key allergen of timothy grass, causing a specific IgE response in more than 90% of sensitized individuals, followed by Phl p 5, affecting 65-90% of patients with grass pollen allergy. Phl p 7 sensitization was not observed in the pediatric population before the age of 5 years and was negligible in adolescents, whereas Phl p 12 sensitization increased with age.

Timothy pollen causes allergic rhinitis (AR), allergic rhinoconjunctivitis (ARC) and asthma in sensitized people. In industrialized countries, AR caused by grass pollen and allergic asthma are one of the main health problems. It has been found that AR usually precedes asthma, and AR itself serves as a risk factor for asthma. The diagnosis of grass pollen allergy is based on clinical history to determine the connexion between grass pollen exposure and symptoms, and confirmation of the relevant allergens for each patient by in vitro testing. 

Determination of specific IgE in human blood to - Timothy grass g6, shows the body's reaction to this allergen.

Analysis method: ImmunoCAP method (Immunofluorescence in the solid phase)

Units of measurement: kU/l

Biomaterial for analysis: venous blood