Package "Hormonal Contraception Planning: Genetic Profile (MTR, MTRR, MTHFR, F II, F V)"
The "Hormonal Contraception Planning" genetic profile is a comprehensive molecular genetic analysis aimed at identifying polymorphisms in the MTR, MTRR, MTHFR (responsible for folate metabolism) and FII, FV (blood clotting factors) genes.
Clinical indications:
- Planning the use of hormonal contraception or hormone replacement therapy.
- Thrombosis or thromboembolism (in the patient's medical history or in close relatives).
- Thromboembolic complications during pregnancy (in the patient's medical history).
- Cardiovascular diseases (coronary heart disease, ischemic stroke, arterial hypertension, atherosclerosis).
Indications based on medical history:
- Family history of: Thrombosis or thromboembolism. Complications during pregnancy (miscarriage, preeclampsia, intrauterine fetal death). Early myocardial infarction or stroke.
- Lifestyle and related factors: Smoking. Long-term use of methotrexate, anticonvulsants, other folic acid antagonists, or drugs that interfere with folate absorption. Stomach and intestinal disorders with impaired vitamin B12 absorption. Kidney disease, hemodialysis. Long-term chronic infections. Unbalanced diet.