Vitamin B6 (pyridoxine) (chromatography)
B6 vitamin is involved in metabolism, it is necessary for normal operation of central and peripheral nervous systems.
Various forms of B6-vitamin are converted to pyridoxal-5-phosphate in the human body.
Pyridoxal-5-phosphate is a part of enzymes involved in decarboxylation, transamination and racemization of amino acids, as well as enzymatic conversion of sulfur-containing and hydroxylated amino acids. It is used in the serotonin synthesis from tryptophan, in methionine, cysteine and other amino acids metabolism. It is also used in the histamine metabolism.
It is involved in many aspects of macronutrients metabolism, synthesis of neurotransmitters (serotonin, dopamine, adrenaline, norepinephrine, GABA), histamine, hemoglobin synthesis and function, lipid synthesis, gluconeogenesis, gene expression.
B6 vitamin (pyridoxine, pyridoxal, pyridoxamine) can be found in many foods. Cereal sprouts, walnuts and hazelnuts, spinach, potatoes and sweet potatoes, carrots, cauliflower and white cabbage, tomatoes, strawberries, cherries, oranges and lemons, avocados are especially rich in it, less in meat and dairy products, fish, eggs, cereals and legumes ... In addition, this vitamin is synthesized by the intestinal microflora.
Vitamin B6 enters the body with food, and it is also synthesized by intestinal microflora.
Symptoms of B6 deficiency in humans are as follows - microcytic anemia, dermatitis, including cheilitis (angular cheilitis), seborrhea and glossitis (tongue swelling), depression, lethargy, confusion, weakened immune status; irritability, heightened hearing, convulsions in children.
Symptoms of excess B6 - severe impairment of motor coordination, painful skin lesions, increased sunlight sensitivity, nausea, epigastric burning.
B6 vitamin test is a liquid chromatographic pyridoxal phosphate blood test.